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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T24116 | GSM-1 | gamma Secretase modulator 1,GSM 1 (enzyme modulator),J2.559.799K | |
GSM-1 is a modulator of γ-Secretase. | |||
T63208 | Aβ-IN-1 | Gamma-secretase | |
Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharma... | |||
T10211 | Aβ42-IN-1 | Others | |
Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM). Aβ42-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ42-IN-1 show... | |||
T10589L | BPN-15606 | Others | |
BPN-15606, an orally active γ-secretase modulator (GSM), significantly reduces Aβ42 and Aβ40 production in SHSY5Y neuroblastoma cells, demonstrating IC50 values of 7 nM and 17 nM, respectively. This compound exhibits fav... |